Open Flask
Tuesday, July 9, 2019

Cyclofeign?

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We came across an interesting compound in Natural Product Reports Hot off the Press today :  This rather precarious-looking [3.2.2...
3 comments:
Monday, April 1, 2019

You heard it here first

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La Jolla, California -- Sources close to Professor Phil "Strongman" Baran inform us that he his quietly announced his surprise ear...
3 comments:
Thursday, February 21, 2019

E-Birch

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Our work on electrochemical Birch reduction was published today . In case you don't want to read the manuscript, here's the Cliff no...
6 comments:
Monday, January 14, 2019

Technique primer: Test tube columns

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As many of you remember, a little over a year ago Phil did a AMA on reddit . On that AMA, a bunch of people requested that we do a post on h...
10 comments:
Sunday, January 13, 2019

11-Step Total Synthesis of Teleocidins B-1–B-4

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Our paper describing the total synthesis of Teleocidins B-1–B-4 is now published in JACS ! I started working on this project in November 20...
8 comments:
Thursday, January 3, 2019

Decarboxylative carboxylation: radiolabeling carboxylic acids the easy way

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Our latest paper, which arose from a collaboration with the radiochemistry team at BMS, describes a new approach to carbon-14 radiolabeling...
1 comment:
Friday, December 21, 2018

Simply Strained: Total Synthesis of Herqulines

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Our recent syntheses of herqulines B and C have been published today in JACS . While the paper describes the direct nature of our final ...
11 comments:
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