Over at BRSMblog theres a good post on the best synthesis ever. Its a discussion I've had around Baran Lab before, and I figured since total synthesis is our jam, people might have something to contribute to his comment section. I already gave him my 3 cents off the top of my head (Heathcock’s daphniphylline work, Corey-Altom synthesis of aspidophytine (this is probably my favorite), Overman’s work on actinophyllic acid). I'm sure I could think of a few others, but I need to run a column.
Happy Tuesday!
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