Well, its Monday morning and the hoods are down at The Scripps Research Institute.Here's a picture of the lab sitting in the hall, reading papers. I decided it was high time to post the past two week's mechanisms.
Ahh benzene! Europeans fear it, I love the smell of it, and it can look like a snake (Figure 1)! What isn't there to love? Not to mention its qualities as a solvent, and its utility in the azeotropic removal of water from ethanol. But what I'm here to discuss today is how we draw benzene (dude, lets be honest, the Armstrong benzene is fantastic). This came up over coffee a few years ago and I decided to formalize it a little bit. If you want to play along, go ahead and draw a benzene yourself, don't think too hard, but pay attention to how you draw it. Twenty-five graduate student and postdoctoral chemists were surveyed for this blog post and the results were compiled and analyzed for your pleasure (after the jump).
According to Sigma-Aldrich, DFES-Na sold out of stock within 1 week of
being listed, and due to the incredible demand, they are targeting
multi-kilo quantities. Metric tons of DFES-Na will likely be needed in
the next 10 years. This is, of course, exciting news for us but we would
also like this blog post to be exciting for you as well. So, we have
put up another video. This one is about Qianghui (first author of the paper describing DFES-Na) running a
difluoroethylation reaction and
hopefully after watching this video, you will be running your own
This is my first ever blog entry, let alone the Baran lab
blog but on all blogs web-wide. I thought this would be a suitable
entry to celebrate this landmark of mine. I (Yoshi) came to the Baran
Lab in 2007 and obtained my PhD last year but I'm staying here longer
for a pet project of mine. And Ana's. And most importantly for those of
you who visit this page for Baran lab news: Phil's vision. Case in
point: we have been writing a book mostly on heterocyclic chemistry and
today is our official launch date. The book is called "The Portable
Chemist's Consultant." This is not a hardcover book but is only offered on the iBookstore; we also have a website dedicated to it.
While you can find the book itself and the sample book in the former,
and cool graphics and a comments page in the latter, on this blog I
decided to put up a quick video of myself talking through the features
of this electronic book while holding up my iPad.
Here is an impromptu
video taken by Phil using his iPhone... he just stormed into my working
area, brought me into his office and said "let's take a video of you
talking about the interactive features of this book. Starting... now."
Maybe one day I'll take a better version of this video that has my iPad
on a more stable platform and without me stuttering, but for now this
will do. I just wanted to showcase here that this is a highly
interactive book with all sections hyperlinked to each other and all
references hyperlinked to the original literature source on the
internet. As well as a lot of Phil Baran videos for those of you who are
not fortunate enough to be in San Diego to attend his heterocycles
class (which started today, coincidentally... or not). Check it out!